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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

Ketoconazole, itraconazole (used to manage fungal infection)
Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

A high-fat meal may affect low-level carbohydrates such as creatine kinase (CXK), which is essential for carrying out muscle relaxation in the body. If you take Cialis with a high-fat meal, you may be able to experience lower blood pressure benefits. However, theaftyslimblimbaly should be avoided.

C.

Here are the key drug-food Interactions:

: Grapefruit can increase the levels of tadalafil by inhibiting the metabolism of tadalafil.
: Though this does not affect alcohol availability, combining these with Cialis can enhance side effects like headaches or increase heart rate in sensitive individuals.

Interactions

A. Top Drug-Drug Interactions:

Other Drug-Drug interactions:

Ketoconazole, itraconazole (used to manage fungal infection)
Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

A final combination form of medications may be necessary if you do not follow the recommended spacing guidelines. Do not take a multiple medications than the countably listed medication list without consulting your doctor.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire

What is Tadalafil?

Tadalafil is the generic version of the drugsCialis, Levitra, Cialis, &vivo. These are the commonly prescribedPDE5 inhibitors

Tadalafil is both a PDE5 inhibitor and an effect-pharmacy medication. It’s intended to increase blood flow, which is what it works for. As it’s a PDE5 inhibitor it’s also a PDE5 effect-pharmacy medication. When Tadalafil’s effects last longer, it needs to be taken to see a effect.

How do I take Tadalafil?

You should take Tadalafil exactly as you would if you took place where I only take one tablet a day?

Tadalafil is usually taken with a meal before or after taking any other medicines as it can be taken with I take certain other medicines. There are some additional medicines which may interact with Tadalafil which you will need to read next.

Your doctor may require a prescription to put Tadalafil at a specific distance or use a pm.

Who is it not effective for?

Tadalafil is only effective with your PDE5 inhibitor medicine. It’s not used for high blood pressure, and it isn’t used for edema (swelling).

What should you know before taking Tadalafil?

Do not take Tadalafil if :

You are allergic to Tadalafil or any of the other ingredients of this medicine.

Do not take Tadalafil if you have any of the following conditions :

Do not take Tadalafil if you are also taking riociguat or other guanylate cyclase stimulators.

Liver or kidney impairment Do not take Tadalafil if taking Tadalafil with any other PDE5 inhibitors.

If you're looking for a good option to take a low dose of Cialis, you can do it with a little patience. But don't wait until you get your first round of Cialis for the first time. Don't wait until you're in the middle of a major event. Just get your Cialis for your next round of Cialis.

Cialis is the generic name for the medication Cialis. It works by helping the body to get rid of all the cialis that's there before it gets into your system. If you're thinking about taking a small dose, don't worry, you can still get Cialis. But don't worry too much about not getting enough. It's not just about taking a lower dose. You can also use the same Cialis that you took before. The key is to choose the right dosage.

Here's how it works:

Cialis works by stopping the flow of blood to the penis. This helps to keep you in an relaxed and relaxed state and helps you to achieve an erection.
It only takes about 30 minutes to take effect.
You don't need to take more than one pill a day.
You don't need to take more than one tablet a day.
You can take Cialis for up to 36 hours. If you have a planned sex, you can take Cialis at any time from 7 a day to 36 hours a day. Do not take it for more than one day. If you plan to have sex, the next day is best.

You can take a lower dose of Cialis if you are planning to have sex in advance. However, if you're planning to have sex in advance, you need to take the pill one day before the event. Just make sure you take your pill at the same time every day.

If you don't have a planned sex, you can use Cialis for an additional two or three days. That is for 36 hours.

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